Smart dosing for IBD: Computer-Guided drug delivery shows promise
NCT ID NCT04835506
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using a computer dashboard to guide infliximab dosing is more effective and safer than standard dosing for people with Crohn's disease or ulcerative colitis. About 124 participants will receive either dashboard-guided or standard treatment, with the goal of achieving and maintaining remission without steroids. The approach aims to better control disease and reduce side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Atrium Health Center for Digestive Health
Charlotte, North Carolina, 28204, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, 03766, United States
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Lahey Hospital and Medical Center
Burlington, Massachusetts, 01805, United States
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LifeSpan Brown University
Providence, Rhode Island, 02915, United States
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London Health Sciences Centre - Children's Hospital
London, Canada
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McGill University Health Centre (MUHC) Montreal General Hospital
Montreal, Canada
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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NYU Langone Health
New York, New York, 10016, United States
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Northwestern University
Evanston, Illinois, 60208, United States
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Rockford GI
Rockford, Illinois, 61107, United States
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University of Chicago Medicine
Chicago, Illinois, 60637, United States
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University of Maryland Medical Center
Baltimore, Maryland, 21201, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Utah
Salt Lake City, Utah, 84132, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 20500, United States
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Weill Cornell Medical College
New York, New York, 10065, United States
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Yale University School of Medicine
New Haven, Connecticut, 06510, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a patient registry unlock the secrets of IBD?
- Can we predict how kids with IBD will respond to treatment?
- Can switching IBD meds heal the gut when symptoms are quiet?
- Can a milk sugar tame IBD symptoms?
- Could an extra flu shot shield vulnerable kids?