New PET tracer could help doctors see inflammation in the body
NCT ID NCT07625345
First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 4 times
Summary
This study tests a new radioactive tracer called [11C]ZTP-1 to see if it can measure a protein called PDE4B in the brain and body. PDE4B helps control inflammation and brain signals. Forty healthy adults will get the tracer and have PET/CT scans. The goal is to see if this tracer can be used in future studies to monitor diseases or treatment effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
11C-ZTP-1 (a radioactive tracer injected intravenously for PET imaging)
What this could lead to
If successful, this tracer could help doctors measure PDE4B levels in the body, potentially improving how they monitor diseases or treatment responses.
What could go wrong
This is an early Phase 1 study with only 40 healthy participants. It is designed to test the tracer's safety and imaging ability, not to treat any disease. The tracer may not work as expected in future studies.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••