Two days of arm rest may reveal why muscles weaken faster in type 2 diabetes

NCT ID NCT06750497

Recruiting now Knowledge-focused Sponsor: Wageningen University Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study investigates how two days of forearm immobilization (keeping the arm in a cast or sling) changes the way muscles take up glucose and amino acids. Researchers will compare these effects in people with type 2 diabetes and healthy volunteers. The goal is to understand why muscle insulin sensitivity drops so quickly during short periods of inactivity, especially in those with diabetes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: forearm immobilization
What this could lead to: If successful, this could help explain why muscle weakness and insulin resistance develop quickly in people with type 2 diabetes after short periods of inactivity.
What could go wrong: This is a small, early-stage study (26 participants) that only looks at short-term effects. Results may not apply to longer periods of inactivity or to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY TYPE 2 DIABETES

Contacts and locations

Locations

Wageningen University and Research
RECRUITING

Wageningen, Gelderland, 6708WD, Netherlands

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