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New brain tracer could light the way to understanding Alzheimer's and Parkinson's

NCT ID NCT07686393

Recruiting now Knowledge-focused Sponsor: National Institute of Mental Health (NIMH) Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 24, 2026 · Updated 13 times

Summary

This study tests a new radioactive tracer called 11C-ARMI in healthy adults aged 18 and older. The tracer is designed to attach to certain chemicals in the brain and light up during PET scans, which could help researchers study diseases like Alzheimer's and Parkinson's. Participants will have PET/CT scans of the whole body or brain, and some will also have an MRI. The goal is to see how well the tracer works and how it spreads in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
11C-ARMI (radioactive tracer)
What this could lead to
If successful, this tracer could help researchers see and measure noradrenaline activity in the brain, potentially leading to better diagnosis and treatment of neurological diseases like Alzheimer's and Parkinson's.
What could go wrong
This is an early Phase 1 study in healthy volunteers, so it only tests safety and imaging properties. The tracer may not work as expected or may not be useful for studying diseases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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