Can losing weight change how your body burns fuel during exercise?
NCT ID NCT05370222
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This study looks at how weight loss changes the way the body uses energy during exercise. Healthy normal-weight adults will either lose weight through diet or have their weight loss simulated using a special treadmill. The goal is to see if real weight loss affects exercise metabolism differently than just carrying less weight. The findings could help tailor diet and exercise advice for people trying to manage their weight.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Dietary weight loss intervention (caloric restriction and dietary rebalancing)
- What this could lead to
- If successful, this could clarify how weight loss alters exercise energy use, potentially informing better weight management and exercise recommendations for healthy individuals.
- What could go wrong
- This is an early-stage, small study (64 participants) focused on healthy normal-weight adults, so results may not apply to other populations. The dietary intervention's effectiveness and adherence could vary, and the simulated weight loss may not fully mimic real metabolic changes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Clermont-Ferrand
Clermont-Ferrand, AURA, 63000, France
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