Scientists uncover how muscles grow and shrink at the protein level

NCT ID NCT06350591

Completed Knowledge-focused Sponsor: Queen's University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how resistance exercise and leg immobilization affect muscle protein production in 15 healthy women aged 18-30. Participants did leg exercises with one leg while the other leg was immobilized. Researchers measured changes in muscle protein synthesis and breakdown to better understand muscle growth and loss. The goal is to inform future treatments for muscle wasting due to aging, disease, or inactivity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help develop better therapies to prevent muscle loss from aging, disease, or disuse.
What could go wrong: This is a small, early-stage study in healthy young women only, so findings may not apply to older adults or people with medical conditions. It is observational and not testing a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

muscular atrophy myostatin-related muscle hypertrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY SKELETAL MUSCLE ATROPHY SKELETAL MUSCLE HYPERTROPHY

Contacts and locations

Locations

School of Kinesiology and Health Studies

Kingston, Ontario, K7L 3N6, Canada

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