New drug SPY001-001 tested in healthy people for first time

NCT ID NCT06448247

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tested the safety and tolerability of a new drug called SPY001-001 in 96 healthy volunteers. Participants received either the drug or a placebo, and researchers monitored side effects and how the drug moves through the body. Since this is a first-in-human study, the main goal is to gather basic safety information, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
SPY001-001

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Spyre Site 1

    Montreal, Quebec, H3P 3P1, Canada

  • Spyre Site 2

    Cypress, California, 90630, United States

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