Healthy volunteers help uncover best way to take experimental drug calderasib
NCT ID NCT06619314
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 study tested how food, different pill forms, and a common heartburn drug (a proton pump inhibitor) change the levels of the experimental drug calderasib in the blood. Fifty-six healthy adults each took a single dose of calderasib under various conditions. The goal was to gather basic information to guide future studies, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Calderasib (also known as MK-1084)
What this could lead to
If successful, this study will help determine the best way to take calderasib (with or without food, and with or without acid-reducing drugs) for future trials.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. The results only show how the drug is processed in the body, not whether it works for any disease.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Celerion (Site 0001)
Lincoln, Nebraska, 68502, United States