New diabetes pill shows promise in early safety trial
NCT ID NCT06869018
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new oral drug called LY3549492 in 92 Japanese volunteers, some with type 2 diabetes and some healthy. The main goal was to check safety and how the body processes the drug. Participants took multiple doses over several weeks, and researchers monitored side effects and drug levels in the blood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LY3549492 (oral drug)
What this could lead to
If successful, this could lead to a new oral medication to help control blood sugar in people with type 2 diabetes.
What could go wrong
This is an early Phase 1 trial focused on safety, not effectiveness. The drug may not work as hoped or could have side effects. Results may not apply to non-Japanese populations.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Research Hospital Tokyo
Shinjuku-ku, 160-0004, Japan
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Hakata Clinic
Fukuoka, 812-0025, Japan
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Medical Corporation Heishinkai OPHAC Hospital
Osaka, 532-0003, Japan
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P-One Clinic
Hachiōji, 192-0071, Japan