CBD safety trial for athletes: could it protect against concussion?

NCT ID NCT06204003

Completed Knowledge-focused Sponsor: University of Regina Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 study tested whether a high-CBD hemp extract is safe for healthy male athletes in contact sports. Thirty-four participants took increasing daily doses of CBD (up to 30 mg per kg of body weight) over several weeks. Researchers monitored brain and heart function, side effects, and how the body processes CBD. The goal was to check safety, not to prove it prevents or treats concussion.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high-CBD cannabis/hemp isolate extract (99% CBD, 0.1% THC)
What this could lead to: If safe, this could support larger studies on CBD for concussion protection and pain management in athletes.
What could go wrong: This is a very early Phase 1 safety study with only 34 healthy athletes. It does not test effectiveness for concussion or pain, and results may not apply to the general public.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY

Contacts and locations

Locations

Pasqua Hospital

Regina, Saskatchewan, S4T 7T1, Canada
University of Regina

Regina, Saskatchewan, S4S 0A2, Canada

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