Scientists scan brains of people with depression and bipolar disorder to spot key differences
NCT ID NCT03898297
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study used brain scans to look at two things in people with depression or bipolar disorder: a glutamate receptor called mGluR5 and the density of connections between brain cells (synapses). Researchers compared 120 participants, including healthy volunteers, using PET and MRI scans. The goal was to better understand how these brain features differ in mood disorders, which could guide future treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Yale University PET Center
New Haven, Connecticut, 06519, United States
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