New pill for weight loss? early safety trial underway

NCT ID NCT05313802

First seen May 27, 2026 · Last updated Jun 23, 2026 · Updated 5 times

Summary

This completed Phase 1 trial tested an oral drug called LY3502970 in 72 healthy overweight and obese adults. The main goal was to check safety and how the body handles the drug. Participants took the drug by mouth and were monitored for up to 42 days. Results will help decide if further studies are warranted.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ICON Early Phase Services

    San Antonio, Texas, 78209, United States

  • ICON Early Phase Services Lenexa Center

    Lenexa, Kansas, 66219, United States

  • Qps-Mra, Llc

    Miami, Florida, 33143, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LY3502970 (oral drug)

What this could lead to

If successful, this could lead to a new oral medication for weight management.

What could go wrong

This is an early Phase 1 trial focused on safety, not effectiveness. The drug may not work for weight loss or could have side effects.

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.