Heart drug may shield bones after menopause
NCT ID NCT04905277
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether atenolol, a widely used beta blocker for heart conditions, can prevent bone loss in postmenopausal women. 420 healthy women aged 50-75 took either atenolol or a placebo daily for a period. The main goal was to see if the drug slowed bone density loss in the hip and lower back.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
atenolol
What this could lead to
If it works, this could point toward a new way to prevent bone loss and fractures in postmenopausal women using a common, inexpensive drug.
What could go wrong
This is a phase 2 trial, so results are still early. The drug may not show a meaningful benefit for bone density, and beta blockers have side effects like fatigue and low blood pressure.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Contacts and locations
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Locations
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Columbia University Irving Medical Center
New York, New York, 10032, United States
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MaineHealth
Scarborough, Maine, 04074, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States