Drug interaction study checks if new compound BI 764198 alters metformin in the body
NCT ID NCT07368569
First seen Jun 24, 2026 · Last updated Jul 07, 2026 · Updated 3 times
Summary
This completed Phase 1 trial in 14 healthy adults tested whether taking BI 764198 along with metformin changes how much metformin gets into the blood. Participants received both drugs together or metformin alone in a crossover design. The goal was to see if there is a drug interaction, which helps guide safe use in future studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BI 764198 and metformin hydrochloride
- What this could lead to
- If successful, this study could help doctors understand whether BI 764198 can be safely combined with metformin in future treatments.
- What could go wrong
- This is a very early, small study in healthy people, not patients. It only looks at drug levels, not whether the combination works for any disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Humanpharmakologisches Zentrum Biberach
Biberach, 88397, Germany
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