Sleepless nights may amplify pain, study suggests

NCT ID NCT06336109

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at how disrupted sleep changes the way healthy adults feel pain and move their joints. Thirty participants received painful injections in the knee and shoulder after a night of fragmented sleep. Researchers measured pain intensity and movement patterns to understand the link between sleep loss and pain sensitivity.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Hypertonic saline injection
What this could lead to
If successful, this could help explain why poor sleep makes pain worse, pointing toward better pain management strategies.
What could go wrong
This is a small, early-stage study in healthy volunteers, not patients. Results may not apply to real-world chronic pain conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain Parasomnias sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aalborg University

    Aalborg, North Denmark, 9000, Denmark

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Other studies related to the condition(s) this trial covers.