New cream aims to fade dark spots naturally
NCT ID NCT05986123
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a cream made from natural plant extracts, niacinamide, and arbutin to see if it safely lightens dark spots (post-inflammatory hyperpigmentation) on the skin. Twenty-five healthy Malaysian adults used the cream twice daily for 20 weeks. Researchers measured changes in skin spots and checked for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Topical cream containing niacinamide, arbutin, Scutellaria Baicalensis Root Extract, Centella Asiatica Extract, and Camellia Sinensis Leaf Extract
What this could lead to
If it works, this could offer a safe, natural option for fading dark spots left after skin injuries or inflammation.
What could go wrong
This was a small, completed study with only 25 healthy adults, so results may not apply to everyone. The cream is cosmetic and not a treatment for any disease.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre
Petaling Jaya, Selangor, 47810, Malaysia