Scientists test if common drugs can stop an LSD trip
NCT ID NCT05964647
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether giving ketanserin, olanzapine, or lorazepam after taking LSD can make the psychedelic effects shorter or weaker. Twenty healthy adults took LSD and then one of these drugs or a placebo. The goal was to see how the drugs changed the intensity and duration of the LSD experience.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LSD, ketanserin, olanzapine, lorazepam
- What this could lead to
- If successful, this could help develop ways to manage or shorten intense psychedelic experiences in therapeutic or emergency settings.
- What could go wrong
- This is a very small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world use, and the drugs tested have their own side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital Basel
Basel, Canton of Basel-City, 4055, Switzerland
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