New male pill aims to stop sperm production

NCT ID NCT03455075

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether a daily oral pill can safely and temporarily lower sperm counts in healthy men to prevent pregnancy. Ninety-two men took either the experimental drug (DMAU) alone, DMAU plus another hormone (LNG), or a placebo for 12 weeks. The goal was to see if sperm concentration could drop below 3 million per milliliter, a level considered effective for contraception.

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Conditions

The condition(s) this trial relates to.

multiple endocrine neoplasia multiple endocrine neoplasia type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center

    Torrance, California, 90509, United States

  • University of Washington Medical Center & Health Sciences

    Seattle, Washington, 98195, United States