New antifungal drug fosmanogepix tested in healthy volunteers

NCT ID NCT06961708

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 trial studied the safety and how the body handles the experimental antifungal drug fosmanogepix in 54 healthy Chinese adults. Participants received single or multiple doses of the drug either by mouth or through an IV, or a placebo. The study measured drug levels in the blood and monitored for side effects to guide future dosing in patients with fungal infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fosmanogepix

What this could lead to

If successful, this study will provide key dosing and safety data for fosmanogepix, potentially supporting its use against serious fungal infections.

What could go wrong

This is an early Phase 1 trial in healthy volunteers, not patients. It only measures safety and drug levels, not whether the drug works against infections.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Xuhui Central Hospital, Longchuan North Road

    Shanghai, 200237, China