Drug interaction check: does itraconazole alter BI 764198 in the blood?

NCT ID NCT07308652

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This completed Phase 1 study in 14 healthy men tested whether taking multiple doses of itraconazole changes the amount of BI 764198 in the blood after a single dose. Participants took BI 764198 alone and then again with itraconazole to compare drug levels. The goal is to understand how these medicines interact, which is important for people who may need both.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Itraconazole and BI 764198
What this could lead to
If successful, this study will show whether itraconazole affects how much BI 764198 gets into the blood, helping guide safe use of both medicines together.
What could go wrong
This is a very early, small study in 14 healthy men, not patients. It only looks at drug levels, not treatment effects or safety in real-world use.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Humanpharmakologisches Zentrum Biberach

    Biberach, 88397, Germany

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