Cold therapy could replace needle numbing for Children's dental work

NCT ID NCT07198022

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether cold application (cryotherapy) works as well as standard numbing gels and sprays to reduce pain from dental injections in children. 100 kids aged 7 to 10 were divided into four groups: one received a lidocaine spray, one a benzocaine gel, one cold distilled water, and one cold lidocaine spray. Researchers measured pain, anxiety, taste, and vital signs to see which method worked best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine, benzocaine, and cryotherapy (distilled water)

What this could lead to

If successful, this could show that cold application (cryotherapy) works as well as numbing gels or sprays for reducing pain from dental injections in children.

What could go wrong

This is a small, completed Phase 4 study with only 100 children, so results may not apply to all kids or settings. Cryotherapy might not be as effective as standard anesthetics for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ondokuz Mayıs University, Faculty of Dentistry

    Samsun, Turkey (Türkiye)