TOPICAL ANESTHESIA
Clinical trials for TOPICAL ANESTHESIA explained in plain language.
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New spray device could replace needles for throat numbing during endoscopy
Symptom relief CompletedThis study tested a new device that numbs the throat and esophagus (OPETA) against standard IV sedation with propofol and ketamine for upper GI endoscopy. 60 adults were enrolled to see which method causes less discomfort and has fewer side effects. The goal is to find a safer, m…
Matched conditions: TOPICAL ANESTHESIA
Phase: NA • Sponsor: Zagazig University • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Cold therapy could replace needle numbing for Children's dental work
Symptom relief CompletedThis study tested whether cold application (cryotherapy) works as well as standard numbing gels and sprays to reduce pain from dental injections in children. 100 kids aged 7 to 10 were divided into four groups: one received a lidocaine spray, one a benzocaine gel, one cold distil…
Matched conditions: TOPICAL ANESTHESIA
Phase: PHASE4 • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Cold or gel? study finds best way to ease Kids' dental injection pain
Symptom relief CompletedThis study tested two ways to reduce pain from dental numbing shots in children. 28 kids aged 6 to 12 received a cold technique on one side of the mouth and a numbing gel on the other side during different visits. Researchers measured pain, heart rate, and oxygen levels to see wh…
Matched conditions: TOPICAL ANESTHESIA
Phase: PHASE3 • Sponsor: Universidad Autonoma de San Luis Potosí • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC