Healthy volunteers help check two zongertinib tablet versions

NCT ID NCT06360081

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed Phase 1 trial tested whether zongertinib tablets made by two different manufacturers are absorbed the same way in the body. Fifty-six healthy adults took a single dose of each version in random order. The goal was to compare drug levels in the blood to ensure the tablets are bioequivalent.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
zongertinib
What this could lead to
If successful, this trial confirms that both versions of zongertinib are interchangeable, supporting reliable manufacturing for future treatments.
What could go wrong
This is an early-phase study in healthy volunteers, not patients. It only measures drug levels in the blood, not effectiveness against any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CRS Clinical Research Services Mannheim GmbH

    Mannheim, 68167, Germany

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