Exercise may shield High-Risk brains from Alzheimer's
NCT ID NCT03876314
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether regular physical activity can improve thinking and memory in middle-aged adults (40-65) who have a family history of Alzheimer's disease. About 180 participants were randomly assigned to an exercise program or a comparison group and were followed for one year. The goal was to see if exercise helps brain function and if a person's genes (APOE4) change the effect.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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University of North Carolina-Greensboro
Greensboro, North Carolina, 27402, United States