Antibiotics may do more than fight infection – new study investigates hidden effects

NCT ID NCT02707042

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how two common antibiotics (amoxicillin and azithromycin) affect the trillions of microbes living in healthy people. Researchers measured changes in metabolism, immune markers, and energy use before, during, and after a short course of antibiotics. The goal was to understand side effects beyond killing bacteria, not to treat any disease. 108 healthy adults aged 18-49 took part.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

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