Healthy men help uncover drug interaction risks

NCT ID NCT07081932

First seen Nov 01, 2025 · Last updated May 26, 2026 · Updated 31 times

Summary

This study looked at how the drug bosentan changes the way the body processes nerandomilast in 16 healthy men. The goal was to see if bosentan speeds up the breakdown of nerandomilast, which could affect how well it works. Participants took bosentan for several days and then a single dose of nerandomilast, with blood samples taken to measure drug levels. The results will help doctors understand if dose adjustments are needed when these drugs are used together.

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Contacts and locations

Locations

  • Humanpharmakologisches Zentrum Biberach

    Biberach, 88397, Germany

Conditions

Explore the condition pages connected to this study.