Scientists track mystery Drug's journey through 6 healthy volunteers

NCT ID NCT06626464

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 1 study from Merck followed 6 healthy adults to see how the drug elpipodect (MK-8189) is absorbed, broken down, and eliminated. Participants took a single oral dose, and researchers measured the drug in blood, urine, and feces over time. The goal was purely to understand the drug's behavior in the body, not to test it for any specific disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Elpipodect (MK-8189)

What this could lead to

If successful, this study will help researchers understand how elpipodect moves through the body, which is a key step toward developing it as a treatment.

What could go wrong

This is a very early, small study in just 6 healthy people. It only looks at how the drug is processed, not whether it works for any disease. Results may not apply to patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Labcorp Clinical Research Unit Inc. (Site 0001)

    Madison, Wisconsin, 53704, United States