Breast milk drug check: HIV med levels measured in nursing moms
NCT ID NCT07086079
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 study enrolled 12 healthy lactating women to measure how much of the HIV drug MK-8591A (doravirine and islatravir) gets into breast milk. Participants took one oral tablet and provided breast milk and blood samples over 24 hours. The goal was to estimate the dose a nursing infant might receive, helping guide future safety recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MK-8591A (doravirine and islatravir combination tablet)
What this could lead to
If successful, this study could help doctors understand whether MK-8591A is safe for breastfeeding mothers and their infants.
What could go wrong
This is a very small, early-stage study in healthy women, not people with HIV. Results may not apply to real-world patients, and the drug could still be unsafe for infants.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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QPS Missouri ( Site 0001)
Springfield, Missouri, 65802, United States