Healthy volunteers needed to set nerve norms for better diagnosis

NCT ID NCT01498211

Completed Knowledge-focused Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to establish normal values for nerve fiber density in the skin using small biopsies from 300 healthy adults aged 20-80. By comparing results across age and sex, researchers hope to improve the accuracy of diagnosing small fiber neuropathy, a condition that affects small nerves. Participants undergo a single 3mm skin punch biopsy from the lower leg.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could provide doctors with a standard reference to better diagnose small fiber neuropathy.

What could go wrong

This is an observational study, not a treatment trial. It only establishes normal values and may not directly improve patient outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY

Contacts and locations

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Locations

CHU de Besançon

Besançon, 25030, France
CHU de Nancy

Nancy, 54035, France
Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France