Healthy volunteers needed to set nerve norms for better diagnosis
NCT ID NCT01498211
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to establish normal values for nerve fiber density in the skin using small biopsies from 300 healthy adults aged 20-80. By comparing results across age and sex, researchers hope to improve the accuracy of diagnosing small fiber neuropathy, a condition that affects small nerves. Participants undergo a single 3mm skin punch biopsy from the lower leg.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could provide doctors with a standard reference to better diagnose small fiber neuropathy.
- What could go wrong
- This is an observational study, not a treatment trial. It only establishes normal values and may not directly improve patient outcomes.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de Besançon
Besançon, 25030, France
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CHU de Nancy
Nancy, 54035, France
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Hôpitaux Universitaires de Strasbourg
Strasbourg, 67091, France
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