Healthy volunteers needed to set nerve norms for better diagnosis

NCT ID NCT01498211

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to establish normal values for nerve fiber density in the skin using small biopsies from 300 healthy adults aged 20-80. By comparing results across age and sex, researchers hope to improve the accuracy of diagnosing small fiber neuropathy, a condition that affects small nerves. Participants undergo a single 3mm skin punch biopsy from the lower leg.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could provide doctors with a standard reference to better diagnose small fiber neuropathy.
What could go wrong
This is an observational study, not a treatment trial. It only establishes normal values and may not directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Besançon

    Besançon, 25030, France

  • CHU de Nancy

    Nancy, 54035, France

  • Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

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