University Hospital, Strasbourg, France

This study tests if freezing desmoid tumors (cryoablation) works better than standard medications for people whose tumors have grown after initial monitoring. About 150 participants aged 13 and older will be randomly assigned to one of the two treatments. The goal is to stop tumo…

This study looks at how well a non-surgical, scope-based treatment works for bile duct injuries that happen during gallbladder or liver surgery. About 220 adults who had such an injury will be treated, and doctors will check if the treatment is successful right away and again aft…

This study looks at whether using one antibiotic or a combination of two antibiotics works better to lower the chance of death in people with a bloodstream infection caused by Enterococcus faecalis bacteria. About 700 adults who had this infection between 2017 and 2023 are includ…

This study looks at two ways to treat multiple sclerosis (MS) in people who were diagnosed after turning 50. One group starts with milder drugs and only switches to stronger ones if needed, while the other group starts with strong drugs right away. Researchers will track which ap…

This study tests a new way to fix a common elbow fracture in children using anchors with sutures instead of traditional screws or pins. The goal is to reduce complications like hardware irritation and the need for a second surgery to remove implants. Nine children under 15 with d…

This study tests whether giving the blood thinner heparin before inserting a tube into the wrist artery (instead of after) can reduce the risk of that artery becoming blocked after a heart procedure. About 550 adults having a heart procedure through the wrist will be randomly ass…

This study is testing whether the antibiotic clindamycin works as well as other drugs for treating Streptococcus infections in artificial joints (periprosthetic infections). Researchers will compare success rates in 260 adults who had surgery for this infection. The goal is to se…

This study looks at whether a simple decision-making flowchart can help general practitioners diagnose vertigo more accurately. Vertigo can be tricky to diagnose, and patients sometimes get the wrong referral. The tool is designed to guide doctors toward the right next step. Rese…

This study looks at whether two checklists (PERC and YEARS) can help doctors decide who really needs a CT scan for a blood clot in the lungs. Researchers will review records of 500 adults from one hospital's ER to see how many scans could have been avoided. The goal is to make di…

This study aims to see how well specially trained dogs can detect bladder cancer just by smelling urine samples. About 340 adults who are scheduled for a bladder exam will provide urine samples for the dogs to sniff. If successful, this could lead to a new, non-invasive way to sc…

This study aims to see if a simple rectal swab test can accurately predict which intensive care unit (ICU) patients will develop serious infections from antibiotic-resistant bacteria. Researchers will enroll 1000 adult patients from a French hospital ICU. The goal is to help doct…

This study looks at whether giving pregnant women free organic vegetables and teaching them about healthy eating can lower their exposure to pesticides. Researchers will compare pesticide levels in urine between women who get the organic food and those who eat normally. The goal …

This study looks at two versions of a surgery (classic vs. modified Nuss technique) for fixing pectus excavatum, a condition where the chest is sunken inward. Researchers will compare 80 teenagers aged 11-18 who had surgery between 2010 and 2024 to see which method leads to short…

This study looks at how the way doctors talk about breech birth affects a mother's decision to have a vaginal delivery or a C-section. About 200 women who gave birth to a breech baby in 2024 at French university hospitals will answer a questionnaire about their satisfaction. The …

This study looks at medical records of 400 adults hospitalized with a severe strep bloodstream infection. The goal is to find out which factors are linked to a higher risk of death within 28 days. By identifying these factors, doctors hope to better predict and prevent fatal outc…

This study looks at whether a continuous glucose monitor (CGM) can spot early problems with transplanted islet cells in people with type 1 diabetes. Researchers will track 36 adults who have already received an islet transplant to see if changes in their glucose levels signal tha…

This study looks at how sleep helps or hurts memory in children with certain types of epilepsy. Researchers will test memory in 95 children with different epilepsy severities and compare them to healthy kids. The goal is to see if epileptic brain activity during sleep causes memo…

This study looks at whether emergency department staff at Strasbourg University Hospital follow best-practice guidelines when using physical restraints on patients. Researchers will review records of 450 adults who were restrained between January and June 2023. The goal is to und…

This study aims to understand why families refuse organ donation when asked, even though most French people support it. Researchers will interview relatives of 100 brain-dead patients to classify their reasons as certain, uncertain, or unknown. The goal is to reduce refusals and …

This study looks at whether a scoring system called the HScore can accurately diagnose a rare overactive immune condition (HLH) in intensive care patients who already have liver failure or cirrhosis. Researchers will review medical records of 100 adults admitted to one hospital o…

This study looks at blood clotting (hemostasis) in 1,000 premature infants born before 37 weeks. Researchers want to find out what normal clotting values are from birth to 18 months, and whether they differ from full-term babies. The goal is to better understand how premature inf…

This study looks back at medical records of 50 adults recently diagnosed with HIV to see if doctors missed warning signs during earlier visits. The goal is to understand why HIV testing wasn't done sooner and how to improve early detection. No new treatments or tests are given—ju…

This study looks at whether giving parents an easy-to-understand information sheet after their child's first simple febrile seizure can reduce worry and unnecessary trips to the emergency room. About 100 children aged 9 months to 5 years who had a first simple febrile seizure wil…

This study looks at whether having a total knee replacement as an outpatient (going home the same day) leads to similar recovery as staying in the hospital. Researchers will compare recovery scores from 440 patients who had the surgery between 2020 and 2023 at a French hospital. …

This study looks at past cases of recurrent borreliosis, a bacterial infection spread by ticks or lice, that were diagnosed in France between 2013 and 2025. Researchers will collect information on symptoms, where patients got infected, the type of bacteria, and how the diagnosis …

This study looks at whether a special questionnaire (called AT HARM 10) can help pharmacists identify when a patient's emergency room visit is caused by a problem with their medications. The goal is to improve treatment and reduce future hospital visits. The study involves 100 ad…

This study looks back at the medical records of 60 adults treated for adrenal cortex carcinoma at a French hospital. Researchers want to learn more about the disease's features and how long patients live after treatment. The goal is to improve future care for this rare cancer.

This study looks back at how antithrombin, a blood protein that helps prevent clots, was prescribed to 160 adult patients in intensive care or operating rooms at Strasbourg University Hospitals over one year. The goal is to see if these prescriptions were appropriate and follow g…

This study looks at the medical records of 115 transgender people who started medical support before age 18 at Strasbourg University Hospital. The goal is to describe their care and experiences. No new treatments are being tested.

This study reviews medical records of 250 adults on blood thinners who came to the emergency room with serious stomach bleeding. Researchers want to see how often doctors use a clotting medicine called prothrombin complex concentrate to stop the bleeding. The goal is to understan…

This study looks at whether certain medications that alter gut bacteria can impact how well immunotherapy works in people with advanced lung cancer. Researchers will review records from 800 adults with stage III-C or IV non-small cell lung cancer who received immunotherapy. The g…

This study is testing a simple questionnaire (called SCST) to measure how severe allergic rhinitis (hay fever) is in patients visiting an ear, nose, and throat (ENT) clinic. About 30 adults with allergic rhinitis will fill out the questionnaire to see if it is easy to use and giv…

This study looks at 100 children who come to the emergency room with visible blood in their urine. The goal is to find out what causes it and how doctors currently manage it. No new treatment is being tested; instead, researchers hope to create a standard care plan based on what …

This study looks at 30 adults with psychotic disorders who are stable on long-term antipsychotics and want to reduce or stop their medication. Researchers will describe each person's real-life experience, including successes and challenges, to better understand when and how depre…

This study tests whether a special type of CT scan (dual-energy CT) can be as accurate as MRI for staging mouth and throat cancers. About 30 adults with these cancers will get both scans, and researchers will compare the results. If the CT works just as well, it could speed up tr…

This study interviews 15 doctors in Alsace who treat frail elderly patients with osteoporosis. The goal is to find out what makes them use (or not use) a practical guide on managing the condition. The results could help improve care and reduce fractures in older adults.

This study reports on one adult with severe hemophilia A who is receiving long-term anticoagulation (blood thinners). The goal is to understand how to balance bleeding risk from the blood thinner with the natural protection against clots from hemophilia. Newer factor VIII therapi…

This study looks at a simple questionnaire called PEN FAST to help doctors choose the right antibiotic for patients who say they are allergic to penicillin-like drugs before orthopedic surgery. Many people are labeled allergic but actually are not, leading to incorrect antibiotic…

This study aims to find out how many adults with cystic fibrosis smoke or vape. Researchers will survey 100 patients at a French hospital. The goal is to improve tobacco prevention and understand how smoking or vaping might affect newer treatments like Kaftrio.

This study looks at how a stay in the intensive care unit (ICU) affects a person's quality of life after leaving the hospital. Researchers want to understand if factors like not remembering the ICU stay can lead to post-traumatic stress disorder (PTSD). They will ask 40 adults wh…

This study looks at 50 adults with unexplained bleeding to see if low serotonin levels in platelets play a role. Researchers will use a bleeding questionnaire and medical records to gather data. The goal is to better understand how serotonin deficiencies affect bleeding risk, not…

This study gathers information from 450 newborns who did not pass their hearing screening. Doctors will check for cytomegalovirus (CMV), a common infection that can cause hearing loss and other health issues. The goal is to better understand how often CMV is found and improve car…

This study looks back at medical records of 100 adults in Alsace, France, who had a confirmed anaplasmosis infection (a tick-borne bacterial disease). The goal is to learn more about how the disease affects people in this region, including symptoms, complications, and death rates…

This study reviews medical records of about 2,450 women who had C-sections at Strasbourg University Hospital between 2021 and 2022. The goal is to understand why some women still feel pain despite spinal anesthesia and how doctors handle it. Findings will help create a better pre…

This study looks at how occupational health doctors and nurses in France identify and refer police officers with mental health difficulties (like depression, anxiety, or PTSD) to specialized care. Researchers will interview 200 health professionals to understand their current pra…

This study looks back at medical records of 30 adults with weakened immune systems (from organ transplants, cancer, or certain medications) who also had toxoplasmosis. The goal is to learn how many people are affected and how to better diagnose, treat, and prevent this infection.…

This study examines whether taking metformin before being admitted to the intensive care unit (ICU) affects survival in patients with severe lactic acidosis. Researchers will review records of 100 adults with type 2 diabetes who were admitted to the ICU with this condition. The g…

This study looks at 500 people who had total knee replacement surgery to see if the type of anesthesia they received—spinal or general—affects how well they recover. Researchers will measure recovery using a questionnaire called QoR-15F. The goal is to find out which method leads…

This study surveys 50 pregnant women at the CMCO to understand their interest and fears about ambulatory (walking) epidural anesthesia. The goal is to learn what patients expect and worry about, so the hospital can better introduce this pain relief option. No treatment is given; …

This study interviews 12 general practitioners in Bas-Rhin, France to find out what makes it hard to care for dying patients at home. Many people wish to die at home, but practical and emotional challenges get in the way. The goal is to understand these barriers and find solution…

This study looks at how patients with transient ischemic attacks (TIAs), or mini-strokes, are diagnosed and treated in emergency departments. Researchers will review records of 300 adults who visited the ER with TIA symptoms in 2024. The goal is to see if care matches each patien…

This study looks at how fatigue and muscle function are connected in people with axial spondyloarthritis, a type of inflammatory arthritis. Researchers will measure exercise capacity and muscle strength in 122 adults starting a new targeted therapy. The goal is to better understa…

This study looks at a newer technique called cryobiopsy, which uses extreme cold to take tissue samples from the lungs. The goal is to see how safe and accurate it is for diagnosing conditions like lung cancer, lymphoma, and scarring lung diseases. About 30 adults will take part …

This study looks at whether teaching delivery room staff how to better find and fix anal sphincter tears during childbirth can lower the chance of women developing anal incontinence later. About 1,000 women who gave birth vaginally at a French hospital will be followed. The goal …

This study looks at using a special ultrasound (liver elastography) to measure liver scarring in children with type III glycogen storage disease, a rare condition that can lead to serious liver problems. Researchers will review past elastography results from 30 participants aged …

This study looks at 50 adults with metastatic bladder cancer who started treatment since October 2024. Researchers want to understand why some patients receive platinum-based chemotherapy instead of the newer Enfortumab Vedotin plus Pembrolizumab combination. The goal is to descr…

This study looks back at 100 adults treated at Strasbourg University Hospital between 2014 and 2023 for a rare condition where an abnormal opening forms between the airway and digestive tract. The goal is to learn how these fistulas were diagnosed and managed, and to track surviv…

This study looks at whether elderly patients (75+) with acute medical problems have better outcomes when they go directly to a regular hospital ward from the emergency room, or when they first spend time in a short-stay unit. Researchers will track 2,000 patients to compare 3-mon…

This study aims to better understand a rare skin inflammation called panniculitis in people with dermatomyositis, a muscle and skin disease. Researchers will observe about 20 patients to describe how this condition looks on the skin and under a microscope. The goal is to gather i…

This study is a survey asking healthcare workers and students in the Alsace region of France about their training and knowledge of organ donation. Researchers want to understand if current education is sufficient and useful, as misconceptions may contribute to transplant shortage…

This study aims to understand what teenage patients and their parents know about hormone replacement therapy for female hypogonadism. Researchers will survey 20 teens aged 11-18 and their parents using questionnaires. The goal is to identify knowledge gaps and create better educa…

This study aims to understand how patients live and recover after surviving acute mesenteric ischemia, a severe and life-threatening abdominal emergency. It will follow 100 adults who were treated for this condition between 2010 and 2022. The main goal is to measure their long-te…