Could a Patient's own blood prevent chronic pain after back surgery?

NCT ID NCT05196503

Recruiting now Prevention Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

About 30% of people who have surgery for a herniated disc still suffer from nerve pain afterward. This study tests whether applying a gel made from the patient's own blood (platelet-rich fibrin) around the nerve during surgery can prevent that chronic pain. The trial will enroll 60 adults scheduled for disc surgery and measure their pain levels afterward.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich fibrin (PRF) made from the patient's own blood
What this could lead to: If it works, this could offer a simple, safe way to prevent long-term nerve pain after disc surgery, reducing the need for painkillers.
What could go wrong: This is a small early-phase trial with only 60 people, so results may not apply to everyone. The treatment might not reduce pain more than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neuralgia Pain, Postoperative radiculopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC POSTSURGICAL PAIN NEUROPATHIC PAIN

Contacts and locations

Locations

Les Hôpitaux Universitaires
RECRUITING

Strasbourg, Bas-Rhin, 67091, France

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