Could painkillers quietly disrupt your hormones?
NCT ID NCT01543425
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This study looks at whether chronic neuropathic pain and the medications used to treat it—like antidepressants, antiepileptics, or opioids—are linked to changes in hormone levels. Researchers will compare hormone levels in 120 adults with chronic pain to healthy volunteers matched by age, sex, and body size. The goal is to see if these hormonal changes might help explain why many pain patients report a lower quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If this study finds that certain pain medications disrupt hormone levels, it could point toward ways to improve quality of life for people with chronic pain.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The findings may not apply to all pain patients, and the results are only a snapshot of hormone levels at one time.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
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