New DNA scanner could solve dystonia mystery for thousands

NCT ID NCT06999096

Recruiting now Diagnosis Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a new, more detailed DNA reading technique (long-read genome sequencing) can find genetic causes of dystonia that standard tests miss. Researchers will analyze blood samples from 150 people with dystonia and their family members. If it works, this could end the long diagnostic journey for many patients and open doors to tailored treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Long-read whole genome sequencing (diagnostic test)
What this could lead to: If successful, this could provide a genetic diagnosis for many people with dystonia who currently have no answers, enabling better counseling and personalized treatment.
What could go wrong: This is an early-stage diagnostic study, not a treatment trial. It may not find new genetic causes for everyone, and the technology is still being validated for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COMBINED DYSTONIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

combined dystonia Dystonia dystonic disorder movement disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMBINED DYSTONIA COMPLEX DYSTONIA DYSTONIA MOVEMENT DISORDERS

Contacts and locations

Locations

CHRU Nancy
RECRUITING

Nancy, 54000, France
CHU de Montpellier - Hôpital Gui de Chauliac
NOT_YET_RECRUITING

Montpellier, 34295, France
Hôpital Pitié Salpêtrière- APHP
NOT_YET_RECRUITING

Paris, 75013, France
Hôpitaux Universitaires de Strasbourg
NOT_YET_RECRUITING

Strasbourg, 67000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.