University Hospital, Strasbourg, France

This study aims to help doctors choose the best antibiotic for surgery patients who say they are allergic to penicillin. Many people are incorrectly labeled with this allergy, which can lead to less effective antibiotic use. Researchers are testing a simple five-question score to…

This French study is testing a new surgical technique for fixing broken elbows in children under 15. Instead of using traditional screws or pins, surgeons are trying special anchors with sutures that may cause less damage to small bone fragments and don't need to be removed later…

This study is testing how well a non-surgical, endoscopic procedure works to repair injuries to the bile ducts that happen during other surgeries. It will enroll 220 adults who have this specific type of injury. The main goal is to see how many patients are successfully treated a…

This study is for people with desmoid tumors that have started growing or causing symptoms after a period of monitoring. It aims to compare two treatment approaches: a procedure that freezes and destroys tumor cells (cryoablation) versus standard drug therapy. The goal is to see …

This study is testing if the antibiotic clindamycin works as well as other standard treatments for serious infections around artificial joints (like hips or knees) caused by Streptococcus bacteria. It will involve about 260 adults who have had this type of infection. Researchers …

This study looks at how doctors at a French hospital manage severe stomach bleeding in patients taking direct oral anticoagulants (DOACs), a common type of blood thinner. Researchers will review the records of 250 adult patients to see how often a clotting agent called prothrombi…

This study looks at whether adults with stable psychotic disorders can safely reduce or stop their long-term antipsychotic medication. Researchers are carefully monitoring 30 patients who want to try taking less medication, often due to side effects. The goal is to learn from rea…

This study looks back at medical records to compare two treatment approaches for people diagnosed with multiple sclerosis after age 50. Researchers want to see whether starting with moderately effective medications or immediately using highly effective treatments works better at …

This study aims to find a better way to monitor people with type 1 diabetes who have received transplants of insulin-producing cells. Researchers will follow 36 patients who have had this transplant to see if data from a continuous glucose monitor (a small wearable sensor) can de…

This study looks back at past surgeries to compare two versions of a common operation for sunken chest (pectus excavatum) in teenagers. Researchers want to see if a newer, modified technique leads to shorter surgery times, less pain after surgery, quicker recovery, or better cosm…

This study aims to find out if using one antibiotic or a combination of two is better for treating a serious blood infection caused by the Enterococcus faecalis bacteria. Researchers will look at 700 adult patients who had this infection to see which treatment approach leads to f…

This study looks at how quickly blood-thinning medications become fully effective in intensive care patients with serious lung clots (pulmonary embolism). Researchers will track 100 patients to see if the time it takes to reach effective blood thinning affects survival, repeat cl…

This study is looking at how well a specific type of knee replacement implant works over time. Researchers will check on 960 patients who had this implant between 2013 and 2024, measuring their pain, knee movement, and ability to walk and climb stairs. The goal is to see if this …

This study is looking at whether a single surgery to replace an infected joint implant works as well as the standard two surgeries for difficult-to-treat Candida yeast infections. It will review the medical records of 16 patients who had this single-surgery approach. The goal is …

This study aims to see if giving a blood-thinning medication (heparin) *before* inserting a tube into the wrist artery for a heart procedure is better at preventing that artery from getting blocked afterward. It will compare this 'early' timing to the usual practice of giving the…

This study is testing whether specially trained dogs can detect bladder cancer by smelling urine samples. Researchers will collect urine from 340 adults scheduled for bladder-related procedures to see how accurately the dogs identify cancer. The goal is to explore if a dog's sens…

This study aims to evaluate the safety and accuracy of a newer lung biopsy technique called cryobiopsy. It will involve about 30 patients with unexplained lung scarring or abnormal lymph nodes in the chest. Researchers will collect data to see if this method provides better diagn…

This study is testing whether a special MRI scan classification system can better tell if an ovarian mass in a girl is cancerous or benign before surgery. It involves 100 girls under 16 who had surgery for an ovarian mass and a pre-surgery MRI. The goal is to help doctors choose …

This study is testing whether a simple flowchart tool can help general doctors better diagnose patients with vertigo (dizziness). Researchers will compare diagnoses made using the tool against those made by ear, nose, and throat specialists. The goal is to improve initial care an…

This study aims to see if checking newborns with unclear hearing test results for a common virus called CMV is helpful. CMV is a leading cause of hearing loss in babies, but most infected babies show no symptoms at birth. By screening these infants, doctors hope to find the cause…

This study aims to see how well a diagnostic scoring system, called the HScore, works for identifying a dangerous immune system overreaction (HLH) in critically ill patients. It will look back at the medical records of 100 adult patients with liver problems who were treated in an…

This study aims to solve a common lab problem: cloudy blood samples from high fat levels can interfere with a critical test that monitors blood-thinning medications. Researchers will test if spinning blood samples at high speed can separate the fat, allowing for accurate measurem…

This study aims to see if a special type of CT scan can work as well as an MRI for diagnosing oral and throat cancers. Currently, patients need both scans, which can delay treatment. Researchers will compare results from both imaging methods in 30 adult patients to determine if t…

This study aims to find out if a new laboratory test called Cryocheck HexLA is better at detecting lupus anticoagulant than the test currently used. Lupus anticoagulant is a substance in the blood that can increase the risk of dangerous blood clots. Researchers will compare the r…

This study is looking at two different methods (called PERC score and YEARS algorithm) to help doctors diagnose pulmonary embolism (blood clots in the lungs) more efficiently in emergency departments. Researchers will review medical records of 500 adults who came to a French hosp…

This study is testing if a city program that gives pregnant women free weekly baskets of organic, local vegetables can lower their exposure to pesticides. Researchers will compare the pesticide levels in the urine of women who receive the food baskets to those who continue their …

This study tests if training delivery room staff to better spot and repair birth tears can prevent long-term anal incontinence in mothers. It will enroll 1,000 women who gave birth vaginally at a French hospital. The goal is to see if this training leads to fewer mothers experien…

This study looks back at 500 patients who had total knee replacement surgery to see if the type of anesthesia they received affected their recovery. Researchers are comparing spinal anesthesia (numbing the lower body) to general anesthesia (being fully asleep) to find out which o…

This study looks at whether patients recover better after knee replacement surgery if they go home the same day (outpatient) versus staying in the hospital. Researchers are comparing the quality of recovery for 440 patients who had their surgery between 2020 and 2023. They want t…

This study aims to understand the different reasons why children come to emergency rooms with visible blood in their urine. Researchers will observe 100 children under 18 years old who arrive at pediatric emergency departments with this symptom. The goal is to gather information …

This study aims to establish what normal blood clotting values are for premature infants. Researchers will look back at medical records from up to 1,000 babies born before 37 weeks to measure clotting factors from birth until they start walking. The goal is to see if these values…

This study is surveying doctors in France to understand their knowledge of tick-borne encephalitis (TBEV), a rare but serious disease. Researchers want to see if doctors in areas where the disease is common know more about it than doctors elsewhere. The goal is to improve early d…

This study looks back at how doctors prescribed antithrombin, a medication that helps other blood thinners work properly, to patients in intensive care at Strasbourg University Hospitals. Researchers will review one year of medical records from 160 adult patients who received thi…

This study aims to understand if certain blood markers related to cell function and stress can help doctors detect and predict the course of pre-capillary pulmonary hypertension. Researchers will follow 120 patients for 3 years, collecting blood samples during routine visits to m…

This study aims to understand if common blood thinners (heparins) interfere with the accuracy of lab tests used to monitor a different blood thinner called argatroban. Researchers will analyze blood samples from 70 adult patients already taking heparin to see if the test overesti…

This study looks back at the medical records of transgender youth who received care before age 18 at a hospital in Strasbourg, France. Researchers want to understand the experiences and characteristics of these young patients. The goal is to gather information that could help imp…

This study aims to understand how a stay in an intensive care unit (ICU) affects a patient's mental health and overall quality of life after they go home. Researchers will survey 40 adult patients who spent more than two days in the ICU to measure their experience and check for s…

This study aims to learn more about toxoplasmosis, a serious infection, in people whose immune systems are weakened by conditions other than HIV. Researchers will look at the medical records of about 30 adult patients treated at a French hospital between 2010 and 2023. The goal i…

This study aims to understand why people with severe spondyloarthritis experience such extreme fatigue and how it relates to actual muscle function. Researchers will follow 122 patients who are starting a new targeted therapy, measuring their exercise capacity, muscle strength, a…

This study aims to understand how epilepsy affects memory during sleep in children. Researchers will compare memory recall after one night's sleep in children with different epilepsy types and healthy children. The goal is to learn if nighttime brain activity in epilepsy disrupts…

This study aims to better understand patterns of oxygen deprivation in newborns by analyzing fetal heart rate recordings from 400 babies born with low blood acidity. Researchers hope to identify clearer warning signs that could help doctors recognize dangerous situations earlier …

This study looks back at the medical records of 800 people with advanced lung cancer who received immunotherapy. Researchers want to see if taking certain common medications that affect gut bacteria in the 3 months before starting cancer treatment influenced how long patients liv…

This study follows children who had advanced genetic testing during pregnancy because ultrasound scans showed potential concerns. Researchers want to see how these children develop after birth and understand whether a negative genetic test result truly means there are no underlyi…

This study aims to understand if tracking the amount of Aspergillus fungus in a patient's blood or lung fluid can help doctors predict how well their treatment is working. Researchers will look back at medical records from 100 adults who had this serious fungal infection to see i…

This study aims to learn more about recurrent borreliosis, a serious bacterial infection spread by ticks or lice that causes fevers and other symptoms. Researchers will observe and describe about 25 cases diagnosed in France to understand where patients were infected, what sympto…

This study aims to gather and describe information about cases of human babesiosis, a rare and sometimes severe tick-borne infection, in France. Researchers will look back at medical records from the past 24 years to understand who gets it, how it presents, how it was treated, an…

This study aims to better understand how Lyme disease affects people who are taking a specific type of medication that weakens part of their immune system. Researchers in France will collect detailed information on symptoms, test results, and treatment history from 100 patients w…

This study aims to understand how dentists in France choose to treat infected baby teeth. Researchers will survey 100 dentists who treat children to learn what treatments they prefer and why. The goal is to map current practices, as there is limited data on how French dentists ha…

This study aims to better understand Polycystic Ovary Syndrome (PCOS) by observing 100 women in France who have the condition. Researchers will measure how common obesity is and look for signs of insulin resistance, which can increase diabetes risk. The goal is to gather detailed…

This study is checking if continuously monitoring oxygen levels while moving patients from the operating room to the recovery room helps catch and prevent low oxygen events. It will involve 30 adults having surgery under general anesthesia. Researchers will compare oxygen reading…

This study is looking at past medical records to understand how doctors currently screen for and treat obstructive sleep apnea in children with Down syndrome. By reviewing the care of 30 children, researchers aim to identify the best practices and create a clear, standardized tre…

This study aims to understand the relationship between alcohol use disorder and weight-loss (bariatric) surgery. Researchers will review the medical records of 20 patients who have had the surgery and also received treatment for alcohol problems. The goal is to see how their surg…

This study aims to understand why families refuse organ donation when their loved ones have died, even though most people support donation. Researchers will interview 100 families at a French hospital to learn their reasons for saying no. The goal is to find ways to reduce refusa…

This study aims to understand if repeated headers in soccer cause subtle brain damage that can be seen on special MRI scans. Researchers will compare brain scans of professional soccer players near the end of their careers with scans of people who don't play contact sports. The g…

This study is observing a single adult patient with severe hemophilia A who is taking long-term blood-thinning medication. Researchers want to understand how to safely manage this combination, as blood thinners increase bleeding risk while hemophilia already causes poor clotting.…

This study aims to understand why patients on ECMO life support machines often have serious bleeding or clotting problems. Researchers will closely track changes in different types of blood platelets in 75 adults with heart or lung failure during their first week on ECMO. The goa…

This study aims to understand how women with Turner Syndrome pursue becoming parents. It will follow 93 women treated at a French hospital who expressed a desire to have children. Researchers will track their journeys through natural pregnancy, egg donation, or adoption to measur…

This study aims to better identify when a patient's trip to the emergency room is caused by a harmful reaction to their medications. Researchers will use a special checklist on 100 older adult patients to spot these medication-related problems. The goal is to understand how often…

This study is a survey asking healthcare professionals and students in the Alsace region of France about their training and experience with organ donation. Researchers want to understand if current education is sufficient and useful, as misconceptions may contribute to transplant…

This study aims to understand how often and why hospital emergency room staff physically restrain patients. Researchers will review 450 cases from a French hospital to see if staff are following the latest safety guidelines. The goal is to gather information to improve practices …

This study aims to find patterns in chest CT scans that can predict whether a patient with a severe lung fungal infection (pulmonary mucormycosis) will recover or not. Researchers will look back at the scans and medical records of about 80 patients treated at a French hospital. T…

This study aims to find out if a patient's level of physical activity before surgery can help predict their risk of complications after an incisional hernia repair. Researchers will look at data from 100 adult patients who had this specific surgery. The goal is to understand if b…

This study aims to better understand Lewy body disease, a brain disorder that causes thinking and behavior problems. Researchers will analyze brain wave patterns from 40 patients who previously had EEG tests, looking for specific activity patterns linked to the disease. The goal …

This study aims to find out if medical students find a new training course acceptable. The course teaches them how to officially certify a patient's death and how to sensitively notify the patient's family. Researchers will ask 20 final-year medical students in France for their f…

This study aims to understand how doctors decide between different first treatments for patients with advanced bladder cancer that has spread. Researchers will observe 50 patients who started treatment since October 2024, collecting information about their health characteristics …

This study looks back at the medical records of women who had cesarean sections to understand how often the spinal anesthesia did not provide enough pain relief. Researchers want to identify what factors make this problem more likely and see how doctors handled it. The goal is to…

This study aims to understand the link between nutrition and outcomes for patients with slow-growing digestive tumors. Researchers will observe 100 adult patients to see how many are malnourished and if their nutritional status is connected to their prognosis. The goal is to gath…

This study aims to understand how care plans are developed for vulnerable adults in palliative care. Researchers will interview about 100 people in French care facilities to learn what helps or hinders the planning process. The goal is to gather knowledge to potentially improve f…

This study is a survey to understand how doctors, midwives, and other healthcare professionals in the Alsace region of France care for women with eating disorders during pregnancy and after giving birth. Researchers want to learn about current practices and knowledge gaps. The go…

This study is testing a new training model for neurosurgeons who operate on brain aneurysms. Surgeons will practice delicate surgical techniques using donated human placentas, as their blood vessels closely resemble those in the brain. The goal is to improve surgical skills in a …

This study looks back at the medical records of 50 people in France who were diagnosed with HIV. Researchers want to see if there were signs of infection or chances for testing in the year before their diagnosis that were missed at their general doctor's office. The goal is to un…

This study is a survey of healthcare professionals in European dialysis centers. It aims to understand how doctors currently measure pressure inside the abdomen during a child's dialysis treatment. The goal is to gather information to help create better, safer standard practices …

This study is looking at whether a painless ultrasound scan (elastography) can reliably measure liver scarring in children and young adults with a rare genetic disorder called Glycogen Storage Disease Type III (GSDIII). Researchers will review the medical records of 30 patients w…

This study aims to better understand a rare cancer of the adrenal glands by looking back at the medical records of 60 patients treated at a hospital in Strasbourg, France. Researchers will collect information on symptoms, test results, and treatment outcomes to learn more about h…

This study aims to understand if pregnant patients are interested in a newer type of epidural that allows more movement during labor, known as ambulatory or 'walking' epidural. Researchers will survey 50 women receiving care at a French maternity hospital to learn about their int…

This study aims to see if a simple rectal swab test can predict which intensive care unit (ICU) patients are at risk of developing serious infections from antibiotic-resistant bacteria. It will enroll 1000 adult patients in a French hospital ICU. The main goal is to measure how w…

This study looks at how doctors explain birth options when a baby is positioned feet-first (breech) near the due date. Researchers want to understand how the way doctors talk about vaginal birth versus planned C-section affects mothers' decisions and satisfaction. They're surveyi…

This study aims to better understand how low levels of a chemical called serotonin inside blood platelets might contribute to unexplained bleeding disorders. Researchers will observe 50 adults who have experienced abnormal bleeding but have normal results on standard clotting tes…

This study is testing a short questionnaire that helps doctors track the severity of hay fever (allergic rhinitis) symptoms. It involves 30 adult patients already being seen for hay fever at a French hospital clinic. The main goal is to see if patients find the questionnaire easy…

This study looks at whether elderly patients (75+) with medical emergencies have better outcomes when admitted directly to a hospital ward versus first going to a short-stay unit. Researchers will track 2,000 patients to see if the initial care location affects their 3-month surv…

This study aims to understand how emergency departments diagnose and manage patients who have had a Transient Ischemic Attack (TIA), often called a 'mini-stroke.' Researchers will review the medical records of 300 adults who visited emergency rooms with TIA symptoms in 2024. The …

This study aims to gather more information about human anaplasmosis, a bacterial infection spread by ticks, in the Alsace region of France. Researchers will look back at the medical records of about 100 adults who were confirmed to have the infection. The goal is to better unders…

This study aims to understand what helps or prevents doctors from using a practical guide for managing osteoporosis in frail elderly patients. Researchers will interview about 15 doctors in the Alsace region of France who have had access to the guide. The goal is to learn how to …

This study looks back at the medical records of 221 patients with advanced melanoma who received immunotherapy between 2013 and 2021. The goal is to find hidden patterns or factors that might predict which patients achieve a complete and lasting disappearance of their cancer. Res…

This study aims to understand how occupational health doctors and nurses in France identify police officers who are experiencing mental health difficulties and refer them to appropriate care. It will involve 200 health professionals who work with the National Police. The goal is …

This study aims to learn more about systemic scleroderma, a rare autoimmune disease, by studying families where more than one member has it. Researchers will recruit 20 adults with the disease who also have a close relative with it. By comparing these 'familial' cases, they hope …

This study aims to understand the challenges family doctors face when caring for terminally ill patients at home. Researchers will interview 12 general practitioners in the Bas-Rhin region of France to identify specific barriers and potential solutions. The goal is to gather insi…

This study aims to compare the risk of heavy bleeding between surgical and medication-based abortions performed between 14 and 16 weeks of pregnancy. It will enroll 50 women at a French hospital to gather safety data. The research seeks to inform medical guidelines and help patie…

This study aims to understand why some patients with severe Streptococcal anginosus bloodstream infections die from it. Researchers will look at the medical records of 400 hospitalized adults who had this infection between 2019 and 2024. The goal is to identify which patient fact…

This study aims to better understand a rare skin condition called panniculitis in people who have dermatomyositis, a muscle and skin disease. Researchers will observe up to 20 patients to describe how this condition looks on the skin and under a microscope. The goal is to gather …

This study aims to understand if there is a connection between sleep disorders and severe vertigo in people with Ménière's disease. Researchers will enroll 100 adults with Ménière's to measure their vertigo disability and assess their sleep patterns. The goal is to gather evidenc…

This study is testing if giving parents a clear information sheet after their child's first simple febrile seizure helps reduce their anxiety and unnecessary future emergency room visits. It involves 100 parents whose young children (9 months to 5 years) had their first seizure t…

This study aims to understand if taking the common diabetes drug metformin before hospital admission affects survival rates for patients in intensive care with a severe condition called lactic acidosis. Researchers will look back at the medical records of 100 adults with type 2 d…

This study aims to find out how many adults with cystic fibrosis smoke or vape, as there is very little data on this topic in France. Researchers will survey 100 adults with cystic fibrosis who receive care at a specialized center in Strasbourg. The goal is to gather real-world i…

This study looks back at 10 years of patient records to understand how doctors at a major French hospital have treated a rare condition where an abnormal connection forms between the airway and digestive tract. Researchers will review the medical files of 100 adults treated betwe…

This study aims to understand how patients live and recover after surviving acute mesenteric ischemia, a severe and life-threatening abdominal emergency. It will follow 100 adults who were treated for this condition between 2010 and 2022. The main goal is to measure their long-te…

This study aims to understand what teens with a hormone deficiency and their parents know about hormone replacement therapy. Researchers will survey about 20 families to learn their current understanding of the treatment's purpose and effects. The goal is to use this information …