Apple a day keeps the allergy away? new trial tests raw apple therapy
NCT ID NCT06771791
First seen Jun 06, 2026 · Last updated Jun 19, 2026 · Updated 4 times
Summary
This study tests whether eating small, increasing amounts of raw apple can reduce mouth allergy symptoms in people who are allergic to both birch pollen and apples. 110 participants will eat either real apple or a placebo over 9 months. The goal is to see if they can tolerate a larger dose of apple without symptoms, potentially offering a simple treatment option.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chu Jean Minjoz
NOT_YET_RECRUITINGBesançon, 25030, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hopital François Mitterrand Chu Dijon
RECRUITINGDijon, 21079, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hopital Maison Blanche Chu Reims
NOT_YET_RECRUITINGReims, 51092, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpitaux Universitaires de Strasbourg
RECRUITINGStrasbourg, France, 67000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
raw apple
What this could lead to
If it works, this could offer a practical way for people with birch-apple allergy to eat raw apples without mouth itching or swelling, improving their quality of life.
What could go wrong
This is a Phase 3 trial, but the treatment is simply eating apple, so the effect may be modest. Allergic reactions during the test are possible, and results may not apply to all apple varieties or other related fruits.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.