Could an allergy drug tame COPD Flare-Ups?

NCT ID NCT07059091

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests if omalizumab (Xolair), an allergy drug, can reduce serious flare-ups in people with COPD who also have allergies. About 334 participants will receive injections of the drug or a placebo for 12 months. The goal is to see if the drug lowers the number of COPD exacerbations that require steroids or hospital visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

omalizumab (Xolair)

What this could lead to

If it works, this could provide a new treatment option to reduce COPD exacerbations in people who also have allergies.

What could go wrong

This is a Phase 2 trial, so it is still early. The drug may not reduce flare-ups as hoped, and side effects from injections are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

allergic disease chronic obstructive pulmonary disease lung disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor College of Medicine

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Columbia University

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cornell University

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Duke University Medical Center

    NOT_YET_RECRUITING

    Durham, North Carolina, 27705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Henry Ford Health

    NOT_YET_RECRUITING

    Detroit, Michigan, 48202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mount Sinai, Icahn School of Medicine

    NOT_YET_RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Jewish Health

    NOT_YET_RECRUITING

    Denver, Colorado, 80206, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern University

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Pacific Northwest Airways - VA Puget Sound Healthcare System, Seattle

    NOT_YET_RECRUITING

    Seattle, Washington, 98108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rush University Medical Center

    NOT_YET_RECRUITING

    Chicago, Illinois, 60612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Temple University

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Alabama

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Arizona- Tuscon

    NOT_YET_RECRUITING

    Tucson, Arizona, 85724, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Florida

    NOT_YET_RECRUITING

    Jacksonville, Florida, 32209, United States

    Contact Phone: •••-•••-••••

    Contact

  • University of Illinois at Chicago

    NOT_YET_RECRUITING

    Chicago, Illinois, 60608, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Iowa

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kansas Medical Center

    NOT_YET_RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of San Francisco

    NOT_YET_RECRUITING

    San Francisco, California, 94143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Vermont

    NOT_YET_RECRUITING

    Colchester, Vermont, 05446, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact