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Tiny nodules in connective tissue may reveal hidden clues about organ health

NCT ID NCT07691112

Knowledge-focused Sponsor: The Touro College and University System Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study looks at Chapman reflex points—small, palpable nodules in connective tissue thought to be linked to internal organ function—in healthy young adults. Researchers examine how often these points occur and whether they are associated with symptoms people may experience. The goal is to better understand these points and their potential role in preventive health assessments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help clarify whether Chapman reflex points are useful for early detection of autonomic or lymphatic issues in otherwise healthy people.
What could go wrong
This is a small observational study in healthy volunteers, so findings may not apply to the general population or to people with specific diseases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

101 people

The number who actually took part.

Started

Mar 2020

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Young adult volunteers recruited from an osteopathic medical school community participated in this cross-sectional observational study. Participants completed a standardized questionnaire assessing demographic characteristics, medical history, lifestyle factors, and recent or recurrent visceral symptoms, followed by a blinded palpatory examination of established Chapman Reflex Point locations performed by a trained investigator. A total of 101 participants were enrolled, with a mean age of 27 years.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Ability to understand the study procedures and provide informed consent. * Willingness to complete a standardized health questionnaire. * Willingness to undergo a blinded palpatory examination of established Chapman Reflex Point locations. Exclusion Criteria: * Individuals younger than 18 years of age. * Inability or unwillingness to provide informed consent. * Inability or unwillingness to complete the health questionnaire. * Inability or unwillingness to undergo the palpatory examination. * Pregnancy. * Incomplete study data or questionnaire responses.

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Conditions

The condition(s) this trial relates to.

autonomic nervous system disorder lymphatic system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autonomic nervous system diseases Chapman reflex points Healthy Lymphatic diseases Somatic dysfunction

Contacts and locations

Locations

  • Touro College of Osteopathic Medicine - Harlem

    New York, New York, 10027, United States

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