Healthy volunteers help uncover drug interactions for KBP-5074

NCT ID NCT04606537

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study looked at how two common drugs—itraconazole (a fungal treatment) and rifampin (an antibiotic)—change the way the body processes KBP-5074, a potential medicine for high blood pressure or kidney disease. Twenty-four healthy adults took a single dose of KBP-5074 alone and then again while also taking itraconazole or rifampin. The goal was simply to measure drug levels in the blood, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KBP-5074

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • QPS Missouri

    Springfield, Missouri, 65802, United States