Kbp Biosciences

This study tested an experimental drug called KBP-5074 in 162 people with moderate-to-severe chronic kidney disease whose high blood pressure was not well controlled. The goal was to see if the drug could safely lower blood pressure and reduce kidney damage. Participants were ran…

This early-stage study tested a single dose of the experimental drug KBP-5074 in 11 people with severe chronic kidney disease, including some on dialysis. The main goal was to check for side effects and how the drug moves through the body. The study was completed, but results are…

This study looked at how the drug KBP-5074 behaves in people with moderate liver impairment compared to healthy adults. Twelve participants received a single dose, and researchers measured drug levels in the blood and monitored for side effects. The goal was to understand if live…

This early-stage study tested the safety and tolerability of a new drug called KBP-5074 in 26 adults, including healthy volunteers and people with mild to moderate kidney impairment. Researchers measured how the drug moves through the body and checked for side effects. The goal w…

This study looked at how two common drugs (itraconazole and rifampin) change the way the body processes KBP-5074. Twenty-four healthy adults took KBP-5074 alone and then with each of these drugs. The goal was to measure safety and how the drug moves through the body, which helps …

This study tested two different forms (tablet vs capsule) of the experimental drug KBP 5074 in 20 healthy adults aged 18 to 45. The goal was to see how the body processes each form and to check for safety. Results will help choose the right dose for future studies.

This study looked at how a single dose of the drug KBP-5074 is absorbed, broken down, and removed from the body in 7 healthy men aged 18 to 55. The goal was to measure the drug in blood, urine, and feces, and to identify its breakdown products. No treatment was given for any dise…

This early-stage study tested a new drug called KBP-5074 in 46 healthy adults to see if it is safe and how the body processes it. Researchers also looked at how food affects the drug. The results will help plan future studies for people with kidney disease and high blood pressure…