Kbp Biosciences

This study tested whether a new drug called KBP-5074 could safely lower high blood pressure in people who also have moderate-to-severe chronic kidney disease. About 162 participants were randomly assigned to receive either one of two doses of the drug or a placebo pill for 84 day…

This early study tested whether a new tablet form of an experimental drug (KBP-5074) behaves the same way in the body as an existing capsule form. Twenty healthy volunteers took single doses of either the tablet or capsule to compare how the drug is absorbed and processed. The go…

This early-stage study aimed to understand how a single dose of the experimental drug KBP-5074 is processed by the body in people with moderate liver impairment compared to healthy people. It involved 12 participants to check for safety and measure drug levels in the blood. The g…

This early-stage study aimed to understand how the body absorbs, breaks down, and eliminates the experimental drug KBP-5074. Seven healthy male volunteers received a single dose containing a tiny, safe amount of radioactive tracer to help track the drug. Researchers measured how …

This early-stage study aimed to check the safety and how the body processes a new oral drug called KBP-5074 in people with severe chronic kidney disease. It involved 11 patients, some on dialysis and some not, to see how they tolerated single doses. The main goal was to gather in…

This early-stage study tested the safety of an experimental drug called KBP-5074 in healthy volunteers and people with mild to moderate kidney problems. Researchers gave increasing doses to 26 participants to see how their bodies handled the drug and to check for side effects. Th…

This early-stage study tested how an experimental drug, KBP-5074, interacts with two other common medications. It involved 24 healthy adults to see if these other drugs change how much KBP-5074 stays in the body. The goal was to gather basic safety information to guide future res…

This was the first study in humans to test a new drug called KBP-5074. Researchers gave single, increasing doses to 46 healthy volunteers to check for side effects and see how the body absorbs and processes the drug. The goal was to gather basic safety information to help plan fu…