Does breakfast change how this heart drug works? small study investigates
NCT ID NCT04958135
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study tested how a high-fat, high-calorie meal affects the way the body processes acoramidis, a drug being developed for a rare heart condition. Eighteen healthy adults took a single dose of the drug either with or without food. The goal was to see if food changes the amount of drug in the blood, which could guide future dosing instructions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- acoramidis
- What this could lead to
- If successful, this study could help determine the best way to take acoramidis (with or without food) for future patients.
- What could go wrong
- This is a very early, small study in healthy people, not patients. It only looks at how food affects drug levels, not whether the drug works or is safe long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Celerion
Lincoln, Nebraska, 68502, United States
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