Drug interaction check: will itraconazole alter BI 1015550 levels?
NCT ID NCT03403439
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 trial tested whether taking the antifungal itraconazole changes how the body processes a single dose of the experimental drug BI 1015550 (Nerandomilast). Sixteen healthy men received the drug alone and then again while on a 12-day course of itraconazole. Researchers measured drug levels in the blood to see if there is a meaningful interaction.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BI 1015550 (Nerandomilast) and itraconazole
- What this could lead to
- If successful, this study will show whether itraconazole changes how the body absorbs BI 1015550, helping guide safe dosing in future trials.
- What could go wrong
- This is a very early, small study in only 16 healthy men, so results may not apply to patients or predict real-world effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Humanpharmakologisches Zentrum Biberach
Biberach, 88397, Germany
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