New heart failure drug MK-2828 put through drug interaction test

NCT ID NCT07431866

First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This completed Phase 1 trial in 41 healthy adults tested whether multiple doses of MK-2828, a potential heart failure treatment, affect how the body processes rosuvastatin and furosemide. The goal was to check for drug interactions that could impact future dosing. The study provides early safety and interaction data but does not test MK-2828's effectiveness for heart failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MK-2828
What this could lead to
If successful, this study could help determine safe dosing of MK-2828 alongside common heart failure medications.
What could go wrong
This is an early-stage drug interaction study in healthy people, not a treatment trial. Results may not predict effectiveness or safety in heart failure patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fortrea Clinical Research Unit Inc ( Site 0001)

    Daytona Beach, Florida, 32117, United States

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