Healthy volunteers test new drug combo absorption

NCT ID NCT07133399

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed Phase 1 trial in 32 healthy adults compared how two different combinations of vicadrostat and empagliflozin are absorbed by the body. It also looked at whether food changes drug levels. Participants received a single dose of each combination in random order. The goal was to measure drug concentrations in the blood, not to treat any condition.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
vicadrostat and empagliflozin combination
What this could lead to
If successful, this could help determine the best way to combine these two drugs for future studies.
What could go wrong
This is a very early, small study in healthy people, not patients. It only measures drug levels, not whether the drugs work for any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CRS Clinical Research Services Mannheim GmbH

    Mannheim, 68167, Germany

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