Will a tablet deliver the same dose as a capsule? a bioavailability showdown

NCT ID NCT06840925

Completed Knowledge-focused Sponsor: Praxis Precision Medicines Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial is testing whether a new tablet form of the experimental drug PRAX-628 is absorbed by the body as well as the existing capsule form. Healthy volunteers will receive a single 40 mg dose of each version on separate occasions, and researchers will compare drug levels in the blood. The goal is to see if the tablet can be used interchangeably with the capsule in future studies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PRAX-628
What this could lead to: If the tablet is absorbed as well as the capsule, it could offer a more convenient or cost-effective way to take this drug in future studies or treatments.
What could go wrong: This is an early-stage trial with only 16 healthy people, so results may not predict effects in patients. The tablet might not be absorbed as well as the capsule, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY

Contacts and locations

Locations

Nucleus Network Melbourne

Melbourne, Victoria, 3004, Australia

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