Cure My Disease

Don't miss your cure!

 Log in / Sign up

New tracer maps brain inflammation in healthy people

NCT ID NCT06398392

Completed Knowledge-focused Sponsor: Prof. Daniele Zullino Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested a radioactive tracer called [18F]PBR111 in 6 healthy adults (3 men, 3 women) to see how it spreads in the body and how much radiation it gives off. The tracer is designed to attach to a protein that appears during brain inflammation, which could help doctors spot conditions like Alzheimer's or multiple sclerosis. The goal was to measure radiation dosimetry and biodistribution using PET/CT scans over 120 minutes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
[18F]PBR111 (radioactive tracer)
What this could lead to
If successful, this could help develop better PET scans to detect brain inflammation in diseases like Alzheimer's or multiple sclerosis.
What could go wrong
This is a very small, early study in just 6 healthy people. It only measures radiation exposure, not treatment effects, so it won't directly help patients yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DOSIMETRY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DOSIMETRY HEALTHY

Contacts and locations

Locations

  • Geneva University Hospital

    Geneva, Switzerland

More trials for these conditions

Other studies related to the condition(s) this trial covers.