Healthy volunteers help uncover drug interaction secrets
NCT ID NCT07439250
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed phase 1 study looked at how the antifungal drug fluconazole changes the way the body handles the experimental cancer drug olomorasib. Fifteen healthy volunteers took olomorasib alone and then with fluconazole, and researchers measured drug levels in their blood. The goal was to understand if fluconazole affects how much olomorasib gets into the bloodstream and how quickly it is eliminated.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
olomorasib (LY3537982) and fluconazole
What this could lead to
If successful, this study will help doctors understand how to safely dose olomorasib when taken with fluconazole, potentially improving treatment for future patients.
What could go wrong
This is a very early, small study in healthy people, not patients. It only measures drug levels in the blood, not whether the drug works or is safe long-term.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Fortrea Clinical Research Unit - Daytona Beach
Daytona Beach, Florida, 32117-5116, United States