Drug interaction study in healthy men tests new compound
NCT ID NCT07211425
First seen Nov 01, 2025
Summary
This completed Phase 1 trial in 14 healthy men tested whether taking itraconazole (a common antifungal) changes how the body absorbs the experimental drug BI 3031185. Participants received a single dose of BI 3031185 alone, then later with multiple doses of itraconazole. The goal was to see if itraconazole affects drug levels, which helps guide future dosing recommendations.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEALTHY are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Humanpharmakologisches Zentrum Biberach
Biberach, 88397, Germany
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BI 3031185 and itraconazole
What this could lead to
If successful, this study could help determine the right dose of BI 3031185 when taken with other drugs that affect the same liver enzyme.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. It only looks at drug levels, not whether the drug works or is safe long-term.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.