Fasting vs. keto vs. both: which diet boosts metabolic health best?

NCT ID NCT07659093

Completed Disease control Sponsor: The University of Tennessee at Martin Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares three dietary approaches—intermittent fasting (16:8 schedule), a clean ketogenic diet (20g carbs per day from whole foods), and a combination of both—in healthy adults. Researchers measure changes in body composition, cholesterol, triglycerides, and blood sugar control. The goal is to see which strategy most improves cardiometabolic markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dietary intervention (clean ketogenic diet and/or intermittent fasting)
What this could lead to: If successful, this could help identify which dietary approach best improves cholesterol, blood sugar, and body composition for metabolic health.
What could go wrong: This is a small, non-randomized analysis of two sequential studies, so results may not apply broadly. Dietary adherence can vary, and long-term effects are not assessed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting metabolic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY KETOGEN-BASED THERAPEUTIC DIET METABOLIC ABNORMALITIES

Contacts and locations

Locations

University of Tennessee at Martin

Martin, Tennessee, 38238, United States

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