Your saliva may determine how bitter coffee tastes
NCT ID NCT01079338
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether the proteins in saliva affect how sensitive healthy men are to the bitter taste of caffeine. Researchers tested healthy male volunteers who do not smoke and have no mouth problems. The goal is to understand why some people perceive bitterness more strongly than others.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- caffeine
- What this could lead to
- If successful, this could help explain why people taste bitterness differently, potentially informing food preferences or dietary choices.
- What could go wrong
- This is a small, early-stage observational study in healthy men only. Results may not apply to women, smokers, or people with oral health issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEALTHY are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Does injection location matter for a new Weight-Loss drug? a trial investigates
- Which medical adhesive stays put longest without itching? a head-to-head test in healthy women.
- Avocado at breakfast: a secret weapon for blood sugar and fullness?
- New eye drop aims to tame ocular pain in early trial
- Could a formula closer to breast milk boost baby development?
- Could a daily probiotic help you feel fuller and eat less?